Target Identification via
Target Discovery
When you have a thorough understanding of the disease of interest but you don’t yet know what compound(s) may prove effective at treating it, you need to first identify a target (receptors, enzymes, proteins, genes or RNA) that can be modulated by a therapeutic agent. This is done by analyzing the molecular and cellular mechanisms that underlie the disease, as well as the signaling pathways and other biological processes that are involved.
The goal of target discovery is to discovery as many potential targets as can be found.
Target Identification via Target Discovery involves:
01
Network Analysis
Use of biological networks that map the interactions between different biological entities such as genes, proteins, and metabolites, identifying key nodes that play important roles in the disease.
02
Pathway Analysis
Use of databases of known pathways and the genes, proteins, and small molecules involved in them to identify pathways that are significantly enriched or dysregulated in a particular disease state or condition.
03
Genetic Analysis
Large datasets of genetic information are fed into machine learning algorithms that apply statistical techniques to identify correlations and patterns in the data, and then use these patterns to make predictions about potential drug targets.
TOP TOOLS for Target Identification via Target Discovery:
Vincere™ Network Analytics
Deep analysis of human genetics data identifies disease-associated pathways and molecular targets ripe for intervention.
- Curated knowledge-graph
- Network AI algorithms
- Data-mining integrations
Open Targets™ Platform & Genetics
Freely-available, open source tools that aggregate multiple public data sources and helps scientists identify and prioritize potential therapeutic drug targets for further investigation.
CureHackers Project Management
Every project executed on CureHackers has its own password-protected project management webpage where all the project materials can be accessed, communications between the client and the freelancer are conducted, and project progress can be tracked.
Contract a Bioinformatician
One of our vetted freelance bioinformaticians can identify targets (receptors, enzymes, proteins, genes or RNA) for your disease of interest with the potential to be modulated by a therapeutic agent.
Your bioinformatician will be armed with proficient usage of one or more of the tools listed above to conduct:
- Network Analysis
- Pathway Analysis
- Genetic Analysis
United States 
Australia 
United Kingdom 